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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL4
All Species:
23.33
Human Site:
S334
Identified Species:
36.67
UniProt:
Q8WUA2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA2
NP_624311.1
492
57225
S334
K
G
G
K
Y
T
K
S
D
F
K
E
Y
E
K
Chimpanzee
Pan troglodytes
XP_527529
607
69328
S449
K
G
G
K
Y
T
K
S
D
F
K
E
Y
E
K
Rhesus Macaque
Macaca mulatta
XP_001084421
492
57172
S334
K
G
G
K
Y
T
K
S
D
F
K
E
Y
E
K
Dog
Lupus familis
XP_541147
492
57155
S334
K
G
G
K
Y
T
K
S
D
F
K
E
Y
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXG3
492
57212
S334
K
G
G
K
Y
T
K
S
D
F
K
E
Y
E
K
Rat
Rattus norvegicus
NP_001101927
357
40656
E207
F
K
G
R
S
A
E
E
V
E
E
I
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506397
487
56623
D330
K
G
G
K
Y
T
K
D
D
F
K
D
Y
E
K
Chicken
Gallus gallus
XP_419663
478
55881
G326
V
A
K
I
K
W
K
G
K
G
G
Q
Y
T
K
Frog
Xenopus laevis
Q6GLX7
477
54856
S316
E
A
E
E
R
K
S
S
R
S
E
E
L
R
R
Zebra Danio
Brachydanio rerio
NP_001121802
454
52864
D302
E
K
A
Y
F
K
M
D
N
V
L
I
D
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651291
653
75452
D334
K
G
R
G
I
E
G
D
Y
R
K
L
D
F
N
Honey Bee
Apis mellifera
XP_001121334
512
60307
F334
K
G
K
G
I
Q
Y
F
N
D
N
E
D
L
E
Nematode Worm
Caenorhab. elegans
NP_492343
427
50388
R277
C
E
I
V
R
D
R
R
S
G
D
S
L
Q
Y
Sea Urchin
Strong. purpuratus
XP_001192414
536
61906
T310
S
G
P
I
I
P
Q
T
G
G
E
S
S
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871A4
494
56481
S331
I
H
V
D
F
S
Q
S
V
S
K
L
S
D
V
Conservation
Percent
Protein Identity:
100
80.8
98.7
98.1
N.A.
96.7
71.9
N.A.
77
80.8
23.5
69.7
N.A.
42.4
48.6
47.5
51.1
Protein Similarity:
100
80.8
98.9
98.7
N.A.
98.1
72.3
N.A.
86.1
89
45.7
81
N.A.
55.9
65.8
65.6
65.4
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
86.6
20
13.3
0
N.A.
20
20
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
93.3
26.6
40
33.3
N.A.
20
33.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
7
0
0
7
0
0
0
0
0
0
0
7
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
7
0
20
40
7
7
7
20
14
0
% D
% Glu:
14
7
7
7
0
7
7
7
0
7
20
47
0
40
14
% E
% Phe:
7
0
0
0
14
0
0
7
0
40
0
0
0
7
0
% F
% Gly:
0
60
47
14
0
0
7
7
7
20
7
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
14
20
0
0
0
0
0
0
14
0
0
0
% I
% Lys:
54
14
14
40
7
14
47
0
7
0
54
0
7
7
47
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
7
14
14
7
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
14
0
7
0
0
0
7
% N
% Pro:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
14
0
0
0
0
7
0
7
0
% Q
% Arg:
0
0
7
7
14
0
7
7
7
7
0
0
0
7
14
% R
% Ser:
7
0
0
0
7
7
7
47
7
14
0
14
14
0
0
% S
% Thr:
0
0
0
0
0
40
0
7
0
0
0
0
0
7
0
% T
% Val:
7
0
7
7
0
0
0
0
14
7
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
40
0
7
0
7
0
0
0
47
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _